CELPURE® HIGH PURITY DIATOMITE FILTER MEDIA

CELPURE® is made with diatomaceous earth, who is fossilized remains of hard-shelled algae. It is the ideal choice when developing new high purity processes with diatomite filter aid.

Characteristics:

Diatomaceous earth (DE) is used in many processes (e.g. cell removal, plasma fractionation) as a filter aid for alluvial filtration. DE is fossilized remains of diatoms. Diatoms are hard-shelled algae. Two different types are known: salt (marine) water and freshwater diatoms. Saltwater DE is less homogeneous and consists of various types of algae skeletons which leads to different characteristics compared to freshwater DE which normally consists of only one type of algae skeletons. DE is also present in filter sheet. De-pending on the retention rate, more or less DE added.

The patented Celpure® manufacturing process is a major advance in filter aid technology. This process produces media that surpasses conventional diatomite filter aids in purity, performance, regulatory support, and finished product consistency.

Celpure® is the ideal choice when developing new high purity processes with diatomite filter aid. Studies show that after replacing conventional diatomite filter aids with Celpure diatomite filter aids, extractable impurities are significantly reduced.

Benefits:
Celpure® has many benefits compared to standard DE grades for the pharmaceutical industry.

• FDA registered plant
• GMP process and change control systems in place
• Very good filtration properties
• Available fin 15 kg Tyvek bags
• A broad range of filter aids for each application
• Full regulatory support

Available Celpure® grades:
Physical properties of Celpure® grades used:

Celpure® grade / Permeability [mDarcy] / Solids removed* [μm] / Surface area[m2/g]

• 65 / 40 - 80 / 690–865 / 6 –7
• 100 / 70 –140 / 0.3–0.45 / 5–6
• 300 / 150 –300 / 0.45–0.6 / 3–4
• 1000 / 750 –1250 / > 1.0 / 1–2